Bioinformatics

The Bioinformatics group is responsible for the provision of bioinformatics expertise and resources to research groups within Rothamsted. We have experience in the development of software tools and application of data integration methods used to support systems and network-based approaches to the analysis of large genetic and genomics datasets. The group supports a wide range of software and databases being used by Rothamsted scientists and collaborates extensively, providing consulting and training in the analysis of molecular biology data, in particular next generation sequencing datasets.

What we do

• RNA-seq analysis (de novo assembly, abundance estimation, normalisation, statistical testing, visualisation)
• SNP discovery (for whole genome re-sequencing or GBS projects)
• Genome assembly and annotation
• Functional annotation of genes
• Data integration and data mining
• Network analysis and visualisation